Endocrine Abstracts

Introduction: The hypothalamic-pituitary-ovarian and/or adrenal axis as well as the autonomous nervous system affect significantly the intensity of menopausal symptoms Pre-existing levels of stress may affect the individual perception of menopausal symptoms. We aimed to evaluate the efficacy of a structured stress management program to reduce levels of stress and severity of climacteric symptoms, in a sample of middle-aged Greek women.Methods: The sample...

Introduction: The coexistence of papillary thyroid cancer (PTC) and medullary TC (MTC) is rare. Previous retrospective studies have shown a prevalence up to 19%. The aim of our study was to assess the prevalence of PTC in patients with sporadic MTC.Methods: This is a single-center retrospective study of an endocrinology outpatient clinic at a Tertiary, General, University Hospital. Patients who had undergone total thyroidectomy with central neck compartm...

Male osteoporosis is a reality and in many cases appears to be secondary to drug administration. Many pharmaceutical agents are related to the appearance of osteoporosis, affecting bone metabolism by multiple and diverse mechanisms.The aim was to describe the case of a patient who presented with male osteoporosis of multiple drug aetiology.A patient, male aged 52 years, an orthodox priest, presented with spontaneous fractures and d...

Thyroid antibodies are a heterogenous group of antibodies with diverse and partly unknown properties. The effect of these antibodies on other organ systems and especially on the renal system is unknown. There is however some evidence that thyroid, in particular thyroglobulin antibodies, may affect renal function and may cause glomerulonephritis and possibly nephrotic syndrome. Nephrotic syndrome may alter thyroxine metabolism, as it affects its renal excretion and its albumin ...

The coexistence of multiple adenomas in endocrine glands has been described in the context of the syndromes of multiple endocrine neoplasia. However, recently the presence of adenomas in multiple endocrine glands has been described in patients not fulfilling the criteria of the syndromes of multiple endocrine neoplasia.The aim was to describe the case of a patient with a pituitary gonadotrophinoma who presented with primary hyperparathyroidism caused by ...

Background: Hemangiomas of the thyroid gland are extremely rare.Case presentation: We report a case of a 78-year-old euthyroid male patient with a primary cavernous hemangioma of the thyroid gland. The patient presented for evaluation of a symptomatic, slowly growing neck mass. He did not have any previous medical history and, moreover, had no history of trauma, FNA or other neck procedures. Ultrasound scan revealed a multinodular goiter and a hypoechoic...

Objective: To investigate the effects of oral natural micronized progesterone on hormonal and metabolic parameters in patients with polycystic ovary syndrome (PCOS) and to answer the clinical question if induction of withdrawal bleeding is a necessity for the comparison of hormonal and metabolic data in PCOS subjects.Design: Prospective clinical study.Setting: Academic medical centre.Population: Twenty eight ...

Introduction: Aging is associated with a decrease in muscle and bone mass, and a gain in fat mass. Similar changes are more pronounced in hypercortisolism. We previously demonstrated that high 8 PM salivary cortisol is independently associated with increased prevalence of radiologic vertebral fractures. We wanted to determine whether salivary cortisol circadian rhythm played also a role on body composition.Material and Methods: Cross-sectional study incl...

IntroductionPrimary hyperparathyroidism (PHPT) is characterized by excessive secretion of parathyroid hormone (PTH) from one or more parathyroid glands. PTH has a central role in the regulation of calcium and phosphate and the classic disorder causes primarily hypercalcemia associated with renal and bone manifestations. Non-classical symptoms are also present including cardiovascular, gastrointestinal, psychiatric, neuro-cognitive disorders. Regarding ca...

IntroductionRecent evidence suggests a possible link between prediabetes and lower density in postmenopausal populations. Moreover, earlier data suggest a link between diagnosis of diabetes and lower levels of bone density in women after the menopausal transition. We aimed to evaluate the possible association between insulin resistance and a diagnosis of lumbar or hip osteoporosis and/or prevalent fractures of the lumbar spine. Met...